Biomedicina, Biotecnología y Salud Pública
Departamento
Massachusetts General Hospital
Boston, Estados UnidosPublicaciones en colaboración con investigadores/as de Massachusetts General Hospital (30)
2022
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Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer´s disease and type two diabetes
Fluids and Barriers of the CNS, Vol. 19, Núm. 1
2020
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Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer’s disease
Nature Communications, Vol. 11, Núm. 1
2019
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Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis
Hepatology, Vol. 70, Núm. 2, pp. 496-510
2017
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Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease
Molecular Neurobiology, Vol. 54, Núm. 5, pp. 3428-3438
2016
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Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease
European Journal of Neuroscience, Vol. 44, Núm. 12, pp. 3056-3066
2013
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Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice
Psychoneuroendocrinology, Vol. 38, Núm. 11, pp. 2462-2475
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Four-dimensional microglia response to anti-Aβ treatment in APP/PS1xCX3CR1/GFP mice
IntraVital, Vol. 2, Núm. 2, pp. e25693
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Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice
Journal of Neuropathology and Experimental Neurology, Vol. 72, Núm. 4, pp. 272-285
2012
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Reducing available soluble β-amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice
Journal of Neuropathology and Experimental Neurology, Vol. 71, Núm. 11, pp. 1009-1017
2010
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Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice
Neurobiology of Aging, Vol. 31, Núm. 12, pp. 2058-2068
2009
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Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575
Molecular Neurodegeneration, Vol. 4, Núm. 1
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Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice
Journal of Neurochemistry, Vol. 109, Núm. 6, pp. 1636-1647
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Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Núm. 10, pp. 4012-4017
2008
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Detection of isolated cerebrovascular β-amyloid with Pittsburgh compound B
Annals of Neurology, Vol. 64, Núm. 5, pp. 587-591
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Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer's disease
Nature, Vol. 451, Núm. 7179, pp. 720-724
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Rapid microglial response around amyloid pathology after systemic anti-Aβ antibody administration in PDAPP mice
Journal of Neuroscience, Vol. 28, Núm. 52, pp. 14156-14164
2007
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A limited role for microglia in antibody mediated plaque clearance in APP mice
Neurobiology of Disease, Vol. 28, Núm. 3, pp. 286-292
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Age-dependent cerebrovascular dysfunction in Tg2576 transgenic mouse model of human cerebral amyloid angiopathy
Journal of Cerebral Blood Flow and Metabolism