Factores que influyen en el desarrollo del cáncer vesical en nuestro entorno. Estudio de casos y controles

Abstract

Bladder cancer is a disease with high incidence and prevalence and is associated with multiple risk factors. The objective of the present study was to determine the risk factors and their influence in the incidence of bladder cancer in our area. We performed a case control observational study to analyse the role of the risk factors in the aetiology of bladder cancer in our patients. The risk factors were: family history of bladder cancer, tobacco, occupation, daily water ingestion, alcohol, pattern of coffee drinking, analgesic use, previous history of urologic disorder. The analysis and comparison of variables were done with Odds ratio, chi-square and logistic regression. Tobacco was the main known etiological factor detected in 85% of cases versus 36% of controls (OR of non smokers 0,099: CI 95% 0,050-0,197;p<0,00). The house building was showed to have the tendency as a risk factor that did not reach statistical significance (16% cases vs 7% controls; OR 2,5; CI 95% 0,993-6,452; p=0,157). The rest of variables were not significant in aetiology of bladder cancer. Logistic regression highlighted tobacco habit as unique variable influencing in the etiology of bladder cancer (exp (B) OR 9,335; CI 95% 4,599- 18,950; sig 0,000). Our study showed the clear influence of tobacco in the aetiology of bladder cancer in our patients. The observed tendency in the house building workers should be evaluated in future studies. Other variables were not significant