Infecciones por el virus de Epstein-Barr y citomegalovirus

  1. Tinoco Racero, I.
  2. Caro Gómez, N.
  3. Rodríguez Leal, M. C.
  4. López Tinoco, Elena
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2014

Título del ejemplar: Enfermedades infecciosas (II): infecciones víricas

Serie: 11

Número: 50

Páginas: 2954-2964

Tipo: Artículo

DOI: 10.1016/S0304-5412(14)70722-X DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

La infección por el virus de Epstein-Barr es la causa más frecuente de la mononucleosis infecciosa. Describimos su diagnóstico y los distintos patrones serológicos que se pueden presentar, así como sus principales complicaciones, relación con el desarrollo de neoplasias, síndromes linfoproliferativos y enfermedades autoinmunes. No existe un tratamiento efectivo. El citomegalovirus es la segunda causa de síndrome mononucleósido, la primera de infección congénita en nuestro medio y presenta gran morbimortalidad en los pacientes inmunodeprimidos, fundamentalmente trasplantados de órganos sólidos, médula ósea e infección por el virus de la inmunodeficiencia humana. Su tratamiento se basa en los antivíricos, sobre todo ganciclovir y valganciclovir. Describimos su manejo, efectos adversos, principales alternativas, nuevos fármacos y profilaxis.

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