Protocolo diagnóstico de la diarrea en el paciente inmunodeficiente

  1. D. Gutiérrez Saborido 1
  2. A. Arizcorreta Yarza 1
  3. M. Montes de Oca Arjona 1
  4. A. Martín Aspas 1
  1. 1 Hospital Universitario Puerta del Mar. Cádiz. España
Revue:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Année de publication: 2016

Titre de la publication: Enfermedades del aparato digestivo (VII) Enfermedades del tubo digestivo. Intestino delgado y grueso

Serie: 12

Número: 7

Pages: 387-391

Type: Article

DOI: 10.1016/J.MED.2016.03.014 DIALNET GOOGLE SCHOLAR

D'autres publications dans: Medicine: Programa de Formación Médica Continuada Acreditado

Résumé

Introduction. For immunocompromised patients, diarrhoea due to HIV infection, transplantation or any condition associated with primary immunosuppression has a similar aetiology than that of immunocompetent patients, although with a number of peculiarities such as increased frequency of certain opportunistic germs. Infectious causes. Infectious diarrhoea in immunocompromised patients has a more severe clinical course, increased probability of severe dehydration and is associated with organ transplant rejection and increased morbidity and mortality compared with immunocompetent patients. There are also specific conditions in immunocompromised patients such as neutropenic enterocolitis. Noninfectious causes. Noninfectious causes are not rare in this group of patients. Drug-induced diarrhoea is a significant problem given that a large portion of immunosuppressants promote diarrhoea. Other noninfectious conditions such as post-transplant lymphoproliferative disease and graft-versus-host disease are also characteristic of patients with transplant-related immunosuppression.

Références bibliographiques

  • Abete JF, Martín-Dávila P. Infección intraabdominal en enfermos inmunodeprimidos. Enferm Infecc Microbiol Clin. 2010;28Suppl2:11-7.
  • Cello JP, Day LW. Idiopathic AIDS enteropathy and treatment of gastrointestinal opportunistic pathogens. Gastroenterology. 2009; 136:1952-65.
  • Krones E, Högenauer C. Diarrhea in the immunocompromised patient. Gastroenterol Clin North Am. 2012;41:677-701.
  • Wilcox CM, Saag MS. Gastrointestinal complications of HIV infection: changing priorities in the HAART era. Gut. 2008;57: 861-70.
  • Angarone M, Ison MG. Diarrhea in solid organ transplant recipients. Curr Opin Infect Dis. 2015;28:308-16.
  • Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med. 2007;357:2601-14.
  • Agarwal S, Mayer L. Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency. Clin Gastroenterol He-patol. 2013;11:1050-63.
La source de données: Dialnet