Protocolo diagnóstico de las alteraciones del potasio de origen endocrinológico

  1. Lara Barea, A. 1
  2. Larrán Escandón, L. 1
  3. López Tinoco, C. 1
  1. 1 Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Universitario Puerta del Mar, Cádiz, España
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2020

Issue Title: Enfermedades endocrinológicas y metabólicas (VII)Patología suprarrenal

Series: 13

Issue: 19

Pages: 1099-1103

Type: Article

DOI: 10.1016/J.MED.2020.10.015 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Abstract

Potassium metabolism disorders, both hypokalaemia and hyperkalaemia, are one of the commonest electrolyte disturbances, particularly in hospitalized patients. In the initial evaluation of the patient with hypo- or hyperkalemia, as well as a general analysis including serum electrolytes, it is essential to carry out a complete clinical history for the identification of risk factors in order to guide other complementary tests, that will allow an approach to the etiological diagnosis. Endocrine diseases that present with potassium disorders are those affecting adrenal glands, mainly hyper- and hypomineralocorticisms due to primary glandular disorders, and those secondary to enzyme deficiencies involving the enzymes participating in glucocorticoids, mineralocorticoids and androgens synthesis in the adrenal gland cortex.

Bibliographic References

  • F. Tejada Alteraciones del equilibrio del potasio: hipopotasemia Rev Clin Med Fam., 2 (3) (2008), pp. 129-133
  • E. Kardalas , S.A. Paschou, P. Anagnostis, G. Muscogiuri, G. Siasos, A. Vryonidou Hypokalemia: a clinical update Endocr Connect., 7 (4) (2018), pp. R135-R146
  • J.W. Funder , R.M. Carey, F. Mantero, M.H. Murad, M. Reincke, H. Shibata, et al. The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline J Clin Endocrinol Metab., 101 (5) (2016), pp. 1889-1916
  • J.D. Blumenfeld , J.E. Sealey, Y. Schlussel, E.D. Vaughan Jr., T.A. Sos, S.A. Atlas, et al. Diagnosis and treatment of primary hyperaldosteronism Ann Intern Med., 121 (11) (1994), pp. 877-885
  • L.K. Nieman , B.M. Biller, J.W. Findling, J. Newell-Price, M.O. Savage, P.M. Stewart, et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline J Clin Endocrinol Metab., 93 (5) (2008), pp. 1526-1540
  • J.C. Hollander-Rodríguez , J.F. Calcert Hyperkalemia. Am Fam Physician, 73 (2) (2006), pp. 283-290
  • R. Vanholder , W. Van Biesen, E.V. Nagler Treating potassium disturbances: kill the killers but avoid overkill Acta Clin Belg., 74 (4) (2018), pp. 215-228
  • De Sequera Ortíz P, Alcazar Arroyo R, Albalate Ramon M. Alteraciones del potasio. En: Lorenzo V, López Gómez JM, editores. Nefrología al día. Disponible en: http://www.nefrologiaaldia.org/es-articulo-trastornos-del-potasio-201.
  • C.P. Kovesdy Updates in hyperkalemia: Outcomes and therapeutic strategies Rev Endocr Metab Disord., 18 (1) (2017), pp. 41-47
  • M.A. Perazella Drug-induced hyperkalemia: old culprits and new offenders Am J Med., 109 (4) (2000), pp. 307-314