Relación entre el consumo de fructosa y el aumento de la obesidad

  1. Eduardo Sánchez Sánchez
Journal:
Metas de enfermería

ISSN: 1138-7262

Year of publication: 2016

Volume: 19

Issue: 9

Type: Article

More publications in: Metas de enfermería

Abstract

Objective: to determine the association between fructose intake and an increase in obesity. Method: a narrative review was conducted, through a search in the main databases, such as: Medline, Cuiden, Scielo, CINAHL and Cochrane Plus Library. The following MesH descriptors were used: “fructose”, “nutrition”, “obesity” and “diet”; and in Spanish, the following DeCS: “fructosa”, “nutrición”, “obesidad” and “dieta”. The limits established were: publication date within the last 15 years, and written in Spanish or English. Results: in total, 519 articles were found, but only 16 of them met the inclusion criteria and were within the limits established: eight original articles and eight systematic reviews. The conclusion in nine articles was that the intake of fructose will lead to an increase in weight and BMI; on the other hand, six articles reached the conclusion that there is no association between these factors, and the results of one of them, conducted by Ebbeling et al. in 2012, state that after an intervention for a reduction in fructose intake, there will be a reduction in weight and BMI during the first year, but no difference will be found at 2-year follow-up. Conclusions: no recommendations can be extracted, and there cannot be a standardization of criteria that present a high level of evidence. The controversy regarding the potential increase in obesity caused by the intake of fructose cannot be solved with the data obtained from this review. It would be very interesting to design studies with a robust methodology, allowing experimental studies with a higher statistical significance, and to conduct meta-analyses with outcomes of higher internal and external validity and reliability.

Bibliographic References

  • Pérez de la Cruz AJ, Luna V, Culebras JM. Nutrición y obesidad. En: A. Gil Hernández (ed.). Tomo IV. Tratado de nutrición. Madrid: Médica Panamericana; 2010. p: 420-43.
  • Sociedad Española para el Estudio de la Obesidad (SEEDO). Consenso SEEDO 2000 para la evaluación del sobrepeso y la obesidad y el establecimiento de criterios de intervención terapéutica. Med Clin. 2000; 115:587-97.
  • Finucane MM, Stevens GA, Cowan MJ, Danaei G, Link JK, Pacioreck CJ, et al. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9-1 million participants. Lancet. 2011; 377:557-657.
  • Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014; 384:766-81.
  • Gutiérrez-Fisac JL, Guallar-Castillón P, León-Muñoz LM, Graciani A, Banegas JR, Rodríguez-Artalejo F. Prevalence of general and abdominal obesity in the adult population of Spain, 2008-2010: the ENRICA study. Obesity Reviews 2012; 13(4):388-92.
  • Sánchez-Cruz JJ, Jiménez-Moleon JJ, Fernández-Quesada F, Sánchez MJ. Prevalence of child and youth obesity in Spain in 2012. Rev. Esp. Cardiol. 2013; 66:371-6.
  • Gómez-Huelgas R, Gómez-Peralta F, Carrillo-Fernández L, Galve E, Casanueva FF, Puig-Domingo M, et al. Hacia un manejo integral del paciente con diabetes y obesidad. Posicionamiento de la SEMI, SED, redGDPS, SEC, SEEDO, SEEN, SEMERGEN y SEMFYC. Rev. Clin. Esp. 2015; 215(9):505-14.
  • González Jiménez E, Aguilar Cordero MJ, García García CJ, García López P, Álvarez Ferre J, Padilla López CA, et al. Influencia del entorno familiar en el desarrollo del sobrepeso y la obesidad en una población de escolares de Granada (España). Nutr Hosp. 2012; 27:177-84.
  • Basciano H, Federico L, Khosrow A. Fructose, insulin resistance and metabolic dyslipidemia. Nutr Metab. 2005; 2:5.
  • Bray GA, Nielsen SJ, Popkin B. Consumption of high fructose corn syrup in beverages may play a role in the epidemic obesity. Am J Clin Nutr. 2004; 79:537-43.
  • Esquivel-Solis V, Gómez-Salas G. Implicaciones metabólicas del consumo excesivo de fructosa. AMC. 2007; 49(4):198-202.
  • Tappy L, Lè K, Tran C, Paquot N. Fructose and metabolic diseases: new findings, new questions. Nutr. 2010; 26:1044-9.
  • Hein GL, Storey M, White J, Lineback DR. Highs and Lows of High fructose corn syrup. A Report form the Center for Food and Nutrition Policy and its Ceres® Workshop. Nutrition Today. 2005; 40:253-6.
  • Schorin MD. High fructose corn syrups. Part 1 and 2. Nutrition Today. 2005; 40:248-52.
  • Raben A, Vasilaras TH, Moller AC, Astrupo A. Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 weeks of supplementation in overweight subjects. Am J Clin Nutr. 2002; 76:721-9.
  • Di Meglio DP, Mattes RD. Liquid versus solid carbohydrate: effects on food intake and body weight. Int J Obes Relat Metab Disord. 2000; 24:794-800.
  • Ludwing DS, Petterson KE, Gortmaker SL.. Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet. 2011; 357:505-8.
  • Bes Rastrollo M, Sánchez Villegas A, Gómez García E, Martínez JA, Pajares RM, Martínez González, MA. Predictors of weight gain in a Mediterranean cohort: the Seguimiento Universidad Navarra Study1. Am J Clin Nutr. 2006; 83:362-70.
  • Berkey CS, Rockett HR, Field AE, Gilman MW, Colditz GA. Sugar-added beverages and adolescent weight change. Obes Res. 2004; 12:778-88.
  • Ebbeling CB, Feldman HA, Chomitz VR, Antonelli TA, Gortmaker SL, Osganian SK, et al. A randomized trial of sugar-sweetened beverages and adolescent body weight. N Engl J Med. 2012; 367: 1407-16.
  • Maier I, Stricker L, Ozel Y, Wagnerberger S, Bischoff S, Bergheim I. A low fructose diet in the treatment of pediatric obesity: a pilot study. Ped Int. 2011; 53(3):303-8.
  • Lustig RH, Mulligan K, Noworolski SM, Tai VW, Wen MJ, Erikin-Cakmak A, et al. Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome. Ped Obes. 2016; 4(2):453-9.
  • Te Morenga L, Mallard S, Mann J. Dietary sugars and body weight: systematic review and meta-analysis of randomized controlled trials and cohort studies. BMJ. 2012; 346:e7492.
  • Malik VS, Popkin BM, Bray GA, Despres JP, Willet WC, Hu FB. Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care. 2010; 33:2477-83.
  • Bray GA, Popkin BM. Calorie-sweetened beverages and fructose: what have we learned 10 years later. Ped Obes. 2013; 8(4):242-8.
  • Kuzma JN, Cromer G, Hagman DK, Breymeyer KL, Roth CL. Foster-Schubert KE, et al. No difference in ad libitum energy intake in healthy men and women consuming beverages sweetened with fructose, glucose, or high-fructose corn syrup: a randomized trial. Am J Clin Nutr. 2015; 102(6):1373-80.
  • Grandjean AC, Reimers KJ, Bannick KE, Haven MC. The effect of caffeinated, caloric and non-caloric beverages on hydratation. J Am Coll Nutr. 2000; 19:591-600.
  • Klurfeld DM, Foreyt J, Angelopoulos TJ, Rippe JM. Lack of evidence for high fructose corn syrup as the cause of the obesity epidemic. Int J Obes. 2013; 37(6):771-3.
  • Olguin Mc, Posadas MD, Revelant GC, Labourdette V, Marinozzi DO, Venezia MR, et al. Efectos del consumo elevado de fructosa y sacarosa sobre parámetros metabólicos en ratas obesas y diabéticas. Rev Chil Nutr. 2015; 42(2):151-6.
  • Toop CR, Muhlhausler BS, O´Dea K, Gentili S. Consumption of sucrose, but not high fructose corn syrup, leads to increased adiposity and dyslipidaemia in the pregnant and lactating rat. J Dev Orig Salud Dis. 2015; 6(1):38-46.
  • Pérez Cruz E, Serralde Zúñiga AE, Meléndez Mier G. Efectos benéficos y deletéreos del consumo de fructosa. Rev Endocr Nutr. 2007; 15(2):67-74.
  • Mendivil CO. Bebidas azucaradas y riesgo de obesidad y diabetes. Revista de ALAD. 2013; 3(1):387-96.
  • Primo J. Niveles de evidencia y grados de recomendación (I/II). Enfermedad inflamatoria intestinal al día. 2003; 2(2):39-42.
  • Marzo Castillejo M, Viana Zulairca C. Calidad de evidencia y grado de recomendación. Guías clínicas. 2007; 7 (1):1-14.