Tumor mülleriano mixto maligno (carcinosarcoma heterólogo) de trompa uterina

  1. Natalia García Gómez 2
  2. Manuel Beltrán Ruiz-Henestrosa 1
  3. José María Báez Perea 1
  4. Susana García Gómez 3
  5. María José Añón Requena 1
  6. Pilar Cabello Torres 1
  1. 1 Hospital Universitario Puerta del Mar

    Hospital Universitario Puerta del Mar

    Cádiz, España

    ROR https://ror.org/040xzg562

  2. 2 Facultad de Medicina. Universidad de Cádiz
  3. 3 Facultad de Medicina. Universidad Complutense. Madrid
Revista Española Patologia

ISSN: 1699-8855

Year of publication: 2005

Volume: 38

Issue: 2

Pages: 109-111

Type: Article

More publications in: Revista Española Patologia


Background: Malignant mixed mullerian tumor is an uncommon neoplasm of the female genital tract. The Fallopian tube is most uncommon site. Patients and Methods: The reported case corresponds to a 66 year old woman with abdominal pain. A total hysterectomy with bilateral salpingo-oophorectomy was performed. Results: The neoplasm distended and distorted the left Fallopian tube. On cut section the tube was filled and expanded by a soft tumor with hemorrhagic areas. Microscopically it was composed of malignant epithelial and stromal elements with foci of cartilaginous and rhabdomyosarcomatous differentiation. Conclusions: Four theories have been put forward to explain the origins of the Fallopian tube carcinosarcomas. C-erbB-2 over-expression in both epithelial and mesenchymal components suggests a common carcinogenic mechanism for both components and supports the conversion-histogenesis hypothesis implicating a dominant role for epithelial component.