Nuevas estrategias y generaciones de analgésicos opioides¿qué se está investigando?

  1. Esperanza Regueras 1
  2. Luis Miguel Torres 2
  3. Ignacio Velázquez 3
  1. 1 Universidad de Navarra
    info

    Universidad de Navarra

    Pamplona, España

    ROR https://ror.org/02rxc7m23

  2. 2 Hospital Puerta del Mar, Cádiz
  3. 3 Hospital de Guadix
Revista:
MPJ Multidisciplinary Pain Journal

ISSN: 2697-2263

Año de publicación: 2023

Número: 1

Tipo: Artículo

DOI: 10.20986/MPJ.2022.1030/2022 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: MPJ Multidisciplinary Pain Journal

Resumen

Los fármacos opioides son indispensables en el tratamiento del dolor moderado-intenso, sin embargo, los efectos adversos pueden limitar su uso especialmente en el tratamiento del dolor crónico. Es de vital importancia encontrar nuevas alternativas terapéuticas que ofrezcan un mejor perfil de seguridad sin reducir la eficacia. En esta breve revisión explicamos cuales son las estrategias de investigación que se están siguiendo para obtener una nueva generación de fármacos que actuando sobre el sistema opioide endógeno ofrezca un mejor perfil de eficacia-seguridad.

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