JUAN ANTONIO
MICO SEGURA
Investigador en el periodo 1978-2021
Centro de Investigacion Biomedica en Red de Salud Mental
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigacion Biomedica en Red de Salud Mental (46)
2024
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Consensus on the detection and management of patients with depression and pain as an associated somatic symptom
Spanish Journal of Psychiatry and Mental Health
2022
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Nerve injury induces transient locus coeruleus activation over time: role of the locus coeruleus-dorsal reticular nucleus pathway
Pain, Vol. 163, Núm. 5, pp. 943-954
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Pain and depression comorbidity causes asymmetric plasticity in the locus coeruleus neurons
Brain, Vol. 145, Núm. 1, pp. 154-167
2021
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Neuropathic pain increases spontaneous and noxious-evoked activity of locus coeruleus neurons
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 105
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Sustained escitalopram administration affects glucose metabolism in the rat brain
European Neuropsychopharmacology, Vol. 51, pp. 1-6
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The prevention of relapses in first episodes of schizophrenia: The 2EPs Project, background, rationale and study design
Revista de Psiquiatria y Salud Mental, Vol. 14, Núm. 3, pp. 164-176
2019
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CIBERSAM: Ten years of collaborative translational research in mental disorders
Revista de Psiquiatria y Salud Mental, Vol. 12, Núm. 1, pp. 1-8
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Monoaminergic system and depression
Cell and Tissue Research, Vol. 377, Núm. 1, pp. 107-113
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Monoamines as Drug Targets in Chronic Pain: Focusing on Neuropathic Pain
Frontiers in Neuroscience, Vol. 13
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Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain
Molecular Neurobiology, Vol. 56, Núm. 6, pp. 4135-4150
2018
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Behavioral effects of combined morphine and MK-801 administration to the locus coeruleus of a rat neuropathic pain model
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 84, pp. 257-266
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Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats
European Journal of Pain (United Kingdom), Vol. 22, Núm. 1, pp. 127-141
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Involvement of 5-HT1A/1B receptors in the antinociceptive effect of paracetamol in the rat formalin test
Neurobiology of Pain, Vol. 3, pp. 15-21
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Opioid and noradrenergic contributions of tapentadol to the inhibition of locus coeruleus neurons in the streptozotocin rat model of polyneuropathic pain
Neuropharmacology, Vol. 135, pp. 202-210
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The complex association between the antioxidant defense system and clinical status in early psychosis
PLoS ONE, Vol. 13, Núm. 4
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The onset of treatment with the antidepressant desipramine is critical for the emotional consequences of neuropathic pain
Pain, Vol. 159, Núm. 12, pp. 2606-2619
2017
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Activation of Extracellular Signal-Regulated Kinases (ERK 1/2) in the Locus Coeruleus Contributes to Pain-Related Anxiety in Arthritic Male Rats
International Journal of Neuropsychopharmacology, Vol. 20, Núm. 6, pp. 463-475
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Discovery and development of tramadol for the treatment of pain
Expert Opinion on Drug Discovery, Vol. 12, Núm. 12, pp. 1281-1291
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Single oral dose of cannabinoid derivate loaded PLGA nanocarriers relieves neuropathic pain for eleven days
Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 13, Núm. 8, pp. 2623-2632
2016
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Comorbid anxiety-like behavior and locus coeruleus impairment in diabetic peripheral neuropathy: A comparative study with the chronic constriction injury model
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 71, pp. 45-56